Researchers from the Indian Institute of Technology-Kanpur have found structural differences between beta-arrestin Isoforms 1 and 2 upon their interaction with receptors. Beta-arrestin is a cellular protein that acts as a universal regulator of GPCRs, and this finding may help in designing novel therapeutic targets.
Scientists have identified a synthetic peptide C5apep derived from and modified based on, C5a sequence- may provide an alternative therapeutic candidate compared to currently used ligands
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