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A New Paradigm for Better Drug Discovery Targeting GPCRs

A New Paradigm for Better Drug Discovery Targeting GPCRs

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Researchers from the Indian Institute of Technology-Kanpur have found structural differences between beta-arrestin Isoforms 1 and 2 upon their interaction with receptors. Beta-arrestin is a cellular protein that acts as a universal regulator of GPCRs, and this finding may help in designing novel therapeutic targets.
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