The nf-core project came about at the start of 2018. Phil Ewels (@ewels) was the head of the development facility at NGI Stockholm (National Genomics Infrastructure), part of SciLifeLab in Sweden.

The NGI had been developing analysis pipelines for use with its genomics data for several years and started using a set of standards for each pipeline created. This helped other people run the pipelines on their own systems; typically Swedish research groups at first, but later on other groups and core genomics facilities too such as QBIC in Tübingen.

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