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The CanRisk Web Tool incorporates the new version of BOADICEA, the Breast and Ovarian Analysis of Disease Incidence and Carrier Estimation Algorithm.

BOADICEA is a comprehensive model that can be used to calculate the future risks of developing breast or ovarian cancer using information on family history, lifestyle/hormonal risk factors, rare pathogenic variants in moderate and high risk breast/ovarian cancer susceptibility genes, common breast/ovarian cancer genetic susceptibility variants (Polygenic Risk Scores) and mammographic density. It can also be used to calculate the likelihood of carrying mutations in the moderate to high-risk genes BRCA1, BRCA2, PALB2, ATM, and CHEK2.

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